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Synthesis of Phenyl‐13C6‐ethene
Author(s) -
Zippi Elizabeth M.
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.501
Subject(s) - chemistry , benzene , divinylbenzene , ammonia , styrene , carbon fibers , nitrogen , proton , nuclear chemistry , organic chemistry , radiochemistry , combinatorial chemistry , copolymer , polymer , materials science , physics , composite number , composite material , quantum mechanics
In an effort to prepare an improved carbon‐rich target material for the accelerator production of 13 N labelled ammonia for use in positron emission tomography (PET), sulfonated poly(styrene/divinylbenzene) has been evaluated. The preparation of this target material using naturally abundant carbon‐12 compounds was investigated in an effort to optimize conditions for the preparation of the analogous carbon‐13 target material which may provide a cost‐effective method for producing nitrogen‐13 labelled ammonia via proton irradiation. As part of this study, phenyl‐13C6‐ethene was synthesized in three steps starting from benzene‐13C6. Copyright © 2001 John Wiley & Sons, Ltd.