Premium
Synthesis of 3 H‐(–)‐galanthamine
Author(s) -
Linnemann Elmar,
Fels Gregor
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.500
Subject(s) - chemistry , bromine , stereoselectivity , lithium (medication) , radiochemistry , sequence (biology) , organic chemistry , catalysis , biochemistry , medicine , endocrinology
3 ‐(–)‐galanthamine (0.881 TBq/mmol) was synthesized via stereoselective reduction of (–)‐narwedine with tritiated L‐Selectride ® . This reaction sequence was favored over an exchange of aromatic bromine with lithium aluminium tritide. Copyright © 2001 John Wiley & Sons Ltd.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom