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Synthesis of deuterium‐labelled 2,5‐Bis(4‐amidinophenyl)furan, 2,5‐Bis[4‐(methoxyamidino)phenyl]furan, and 2,7‐diamidinocarbazole
Author(s) -
Stephens Chad E.,
Patrick Donald A.,
Chen Heidi,
Tidwell Richard R.,
Boykin David W.
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.444
Subject(s) - furan , chemistry , deuterium , bromobenzene , biphenyl , medicinal chemistry , stereochemistry , organic chemistry , catalysis , physics , quantum mechanics
The syntheses of 2,5‐bis(4‐amidinophenyl)furan‐ d 8 ( 1‐ d 8 ) and 2,5‐bis[4‐(methoxyamidino)phenyl]furan‐ d 8 ( 2‐ d 8 ) from bromobenzene‐ d 5 in six steps, and of 2,7‐diamidinocarbazole‐ d 6 ( 3‐ d 6 ) from biphenyl‐ d 10 in five steps, are described. Copyright © 2001 John Wiley & Sons, Ltd.