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Manual vs automated 68 Ga‐radiolabelling—A comparison of optimized processes
Author(s) -
Meisenheimer Michael,
Kürpig Stefan,
Essler Markus,
Eppard Elisabeth
Publication year - 2020
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.3821
Subject(s) - chemistry , reproducibility , reliability (semiconductor) , radiochemistry , production (economics) , process (computing) , medical physics , chromatography , computer science , power (physics) , physics , quantum mechanics , economics , macroeconomics , operating system
A critical factor for clinical practice is the production of 68 Ga radiopharmaceuticals manufactured manually or through an automated procedure. 68 Ga radiopharmaceuticals are often prepared manually, although this method can lead to an increased operator's radiation dose and potential variability within production. The present work compares 68 Ga‐radiolabelling (PSMA‐11; DOTA‐TOC) utilizing a cassette module (GAIA; Elysia‐Raytest; Germany) with a manual setup for routine clinical production with regard to process reliability and reproducibility.