An efficient synthesis of trace amine‐associated receptor agonist [1‐ 14 C]tyramine | Zendy

Filer Crist N. | Zendy; Orphanos Demetri | Zendy

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An efficient synthesis of trace amine‐associated receptor agonist [1‐ 14 C]tyramine

Author(s) -

Filer Crist N.,

Orphanos Demetri

Publication year - 2019

Publication title -

journal of labelled compounds and radiopharmaceuticals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 47

eISSN - 1099-1344

pISSN - 0362-4803

DOI - 10.1002/jlcr.3671

Subject(s) - chemistry , tyramine , hydrochloride , agonist , amine gas treating , high performance liquid chromatography , phenethylamine , chemical synthesis , trace amounts , chromatography , combinatorial chemistry , organic chemistry , stereochemistry , receptor , biochemistry , in vitro , medicine , alternative medicine , pathology

The 2‐step synthesis of [1‐ 14 C]tyramine hydrochloride is described with the product being characterized by TLC, HPLC, and UV spectroscopy. Several methods are provided to purify [1‐ 14 C]tyramine hydrochloride, and its storage and stability are also discussed.

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