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Synthesis of [ 15 N ]‐cholamine bromide hydrobromide
Author(s) -
Szeto Judy,
Lemoine Remy,
Nguyen Rosary,
Olson Lori L.,
Tanga Mary J.
Publication year - 2018
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.3598
Subject(s) - chemistry , hydrobromide , bromide , isotope , radiochemistry , combinatorial chemistry , stereochemistry , organic chemistry , physics , quantum mechanics
[ 15 N]‐Cholamine is an isotope tag for metabolomics research, because it possesses 2 important properties: an NMR active isotope and a permanent charge for MS sensitivity. Here, we present a scalable synthesis of [ 15 N]‐cholamine.
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