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Synthesis of isotopically labelled 2‐isopropylthioxanthone from 2,2′‐dithiosalicylic acid and deuterium cumene
Author(s) -
Fang Chao,
Yang Weicheng,
Yang Chao,
Wang Haoran,
Sun Kai,
Luo Yong
Publication year - 2016
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.3400
Subject(s) - chemistry , deuterium , natural abundance , mass spectrometry , cumene , abundance (ecology) , radiochemistry , isotope , tritium , carbon 13 , proton , chromatography , organic chemistry , nuclear physics , benzene , physics , fishery , biology
Two efficient synthetic routes of stable deuterium labelled 2‐isopropylthioxanthone were presented with 98.1% and 98.8% isotopic abundance in acceptable yields and excellent chemical purities. Their structures and the isotope‐abundance were confirmed according to proton nuclear magnetic resonance and liquid chromatography–mass spectrometry.