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Endogenous compounds labeled with radionuclides of short half‐life—some perspectives
Author(s) -
Långström B.,
Karimi F.,
Watanabe Y.
Publication year - 2013
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.3033
Subject(s) - endogeny , chemistry , positron emission tomography , asset (computer security) , biochemistry , neuroscience , psychology , computer science , computer security
In the article, the strategy and synthesis of some endogenous compounds labeled mainly with 11 C are presented. There are some examples illustrating how endogenous labeled compounds in connection with positron emission tomography have unique properties to describe various biological processes, and a few examples of the use of tracers labeled with 13 N and 15 O are also discussed. Labeled endogenous compounds may be an important asset to describe the conditions and the status of biological systems and might therefore be a key for the future search of individualized medicine. Copyright © 2013 John Wiley & Sons, Ltd.