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Preparation du phenyl‐3 propene‐2 OL‐1 14 C‐3 (alcool cinnamique 14 C‐3)
Author(s) -
Hoellinger H.,
Pichat L.
Publication year - 1975
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590110408
Subject(s) - cinnamyl alcohol , yield (engineering) , cinnamic acid , chemistry , hydride , propene , alcohol , column chromatography , aluminum hydride , medicinal chemistry , nuclear chemistry , organic chemistry , catalysis , cinnamaldehyde , materials science , hydrogen , metallurgy , methoxide
Methyl cinnamate ‐3‐ 14 C is reduced smoothly in excellent yield to cinnamyl alcohol ‐3‐ 14 C by aluminum hydride. without attack of the double bond. After purification by column chromatography cinnamyl alcohol ‐3‐ 14 C is obtained with a radioactive overall yield of 65% based on cinnamic acid ‐3‐ 14 C, specific activity = 9 mCi/mM.