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Synthesis of 2‐pyrrolidinone‐5‐ 14 C
Author(s) -
Villani A. J.,
Mendelson W. L.,
Blackburn D. W.
Publication year - 1973
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590090208
Subject(s) - cyanide , yield (engineering) , potassium cyanide , chemistry , potassium , radiochemistry , nuclear chemistry , organic chemistry , materials science , metallurgy
A convenient synthesis of the pharmacological intermediate 2‐pyrrolidione‐5‐ 14 C, was developed using potassium cyanide 14 C as starting material. Potassim cyanide‐ 14 C was converted to 2‐pyrrolidinone‐5‐ 14 C in an overall 56% radiochemical yield.