Premium
Radiochemical syntheses. Part III (1) ‐ the synthesis of tritiated α‐ecdysone and 25‐ deoxy‐α‐ecdysone of high specific activity (2)
Author(s) -
Hafferl W.,
Wren D. L.,
Marshall J. P.,
Calzada M. C.,
Siddall J. B.
Publication year - 1972
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590080111
Subject(s) - ecdysone , tritium , chemistry , radiochemistry , ethanol , palladium , catalysis , stereochemistry , organic chemistry , biochemistry , hormone , physics , nuclear physics
23, 24‐ 3 H‐α‐ecdysone and 23, 24‐25‐ 3 H‐25‐deoxy‐α‐ecdysone were prepared by catalytic hydrogenation of 2ß, 3α, 14α, 22R, 25‐pentahydroxy‐5β‐cholest‐7‐en‐23‐yn‐6‐one with tritium gas and palladium on charcoal in ethanol. Radioactivity and purity measurements of the stored highly labelled compounds are described.