Premium
Synthèse du méthylène‐24 cholestérol 28− 14 C
Author(s) -
Bottin Jean,
Marcel Fétizon Et
Publication year - 1971
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590070316
Subject(s) - methylene , chemistry , alcohol , medicinal chemistry , carbonate , ene reaction , stereochemistry , organic chemistry
A synthesis of 24‐methylene cholesterol, labelled at C 28 , is described. The key intermediate is 3β‐t‐butoxy‐chol‐5‐ene‐24‐al, which is formed by silver carbonate oxidation of the corresponding primary alcohol.