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Labelling of 1‐benzyl‐1‐(3′‐dimethylaminopropoxy)‐cycloheptane fumarate (active substance of the drug Halidor®) with 14 C isotope
Author(s) -
Bánfi D.,
Volford J.,
Pallos L.,
Zólyomi G.
Publication year - 1971
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590070111
Subject(s) - labelling , moiety , cycloheptane , chemistry , isotopes of carbon , carbon fibers , isotope , stereochemistry , organic chemistry , ring (chemistry) , materials science , biochemistry , physics , quantum mechanics , composite number , total organic carbon , composite material
In order to study the pharmacological properties and mode of action of 1‐benzyl‐1‐(3′‐dimethylaminopropoxy)‐cycloheptane fumarate its labelling was performed with 14 C. The radioactive carbon has been introduced into the benzyl group and into the dimethylamino moiety of the dimethylaminopropoxy side chain. The chemical and radiochemical purity of the two isotopic isomers was proved by thin layer chromatography and autoradiography.