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The synthesis and chromatographic behavior of D‐mannitol‐1‐ 14 C‐1‐PO 4 , D‐mannitol‐1‐ 32 PO 4 and 32 PPA
Author(s) -
McGuinness E. T.,
Beebe J. L.
Publication year - 1967
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590030510
Subject(s) - mannitol , phosphate , d mannitol , chemistry , chromatography , polyol , sephadex , organic chemistry , polyurethane , enzyme
In the course of an investigation dealing with the utilization of D‐mannitol and inorganic phosphate by Absidia glauca it was found necessary to confirm the existence and establish the identity of the 1‐Phosphate ester of this polyol. This paper describes the synthesis of radioactive mannitol‐1‐phosphate labeled with carbon‐14 and phosphorus‐32 by a modification of the procedure of Seegmiller and Horecker (1951) for the synthesis of glucose‐6‐phosphate. In addition we document the paper and gel chromatographic behavior on Sephadex G‐15 of the products and 32 PPA prepared by the method of Bell (1948) for the synthesis of polyphosphoric acid.