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Comparison of T‐recoil and Wilzbach labeling of methylamine (preparation of methylamine‐CH 2 T)
Author(s) -
Cipollini R.,
Stöcklin G.
Publication year - 1966
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590020406
Subject(s) - methylamine , anhydrous , yield (engineering) , chemistry , radiochemistry , tritium , methylamines , nuclear chemistry , materials science , organic chemistry , physics , nuclear physics , metallurgy
Recoil labeling of methylamine via the 6 Li(n,α) T‐reaction, using solutions of LiBr in liquid anhydrous methylamine, leads to a 10% radiochemical yield of methylamine‐CH 2 T. The yield is independent of the accompanying radiation dose within a wide range, thus allowing high‐dose pile irradiation. Specific activities up to 100 μC/mM can easily be obtained. For comparison Wilzbach labeling of gaseous methylamine has also been studied. Here, in contrast, poor tritium incorporation is observed, the L‐value for methylamine‐CH 2 T being 2.3 × 10 −2 .