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Preparation of formaldehyde by photochemical condensation of carbon monoxide and tritiated hydrogen, and the synthesis of a tritiated morphine derivative
Author(s) -
Lane A. C.,
McCoubrey A.,
Peaker R.
Publication year - 1966
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590020306
Subject(s) - chemistry , formaldehyde , tritium , tritiated water , carbon monoxide , hydrogen , carbon 14 , radiochemistry , derivative (finance) , condensation , labelling , photochemistry , organic chemistry , catalysis , biochemistry , physics , quantum mechanics , nuclear physics , financial economics , economics , thermodynamics
Tritiated formaldehyde, required for labelling 6: 14‐endo‐etheno‐7‐(2‐hydroxy‐2‐butyl)‐tetrahydro‐oripavine ( M99 ), was prepared by photochemical condensation of carbon monoxide and tritiated hydrogen. The specific activity of the M99 ( 48 C/mmole ) was about one half that of the source of isotope. The loss was traced to undefined secondary decompositions during the photochemical reaction.