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Comparison of carbon‐11 and fluorine‐18 labeled (N‐methyl)benperidol (NMB) in rodents using micropet imaging
Author(s) -
Moerlein S. M.,
Perlmutter J. S.,
Engelbach J.,
Sharp T.,
Kim J. Y.,
Rowland D.,
Laforest R.,
Mody P.,
Patel G.,
Lechner K.,
Welch M. J.
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.25804401160
Subject(s) - chemistry , neuroimaging , pet imaging , radiochemistry , tracer , nuclide , positron emission tomography , nuclear medicine , neuroscience , psychology , medicine , nuclear physics , physics
MicroPET imaging studies with [ 11 C]NMB or [ 18 F]NMB in rats and mice were used to evaluate the methodology as a tool for radiopharmaceutical tracer development. Brain imaging studies show that the technique is useful with both nuclides and both species of rodent. MicroPET hold great promise for future application in neuroimaging research.