Premium
Synthesis of 14 C‐labeled eschenmoser's salt: Dimethyl([ 14 C]methylene)ammonium iodide
Author(s) -
KupczykSubotkowska Lidia,
Shine Henry J.
Publication year - 1993
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580330408
Subject(s) - chemistry , methylene , iodide , ammonium , salt (chemistry) , ammonium iodide , radiochemistry , nuclear chemistry , organic chemistry
A six step synthesis of dimethyl([ 14 C]methylene)ammonium iodide (Eschenmoser's salt) is described. Sodium [2‐ 14 C]acetate was used as the starting material. The overall yield of the final product was 30% with specific activity 8 mCi/mol.