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Practical synthesis of 14 C S‐ribosyl‐l‐homocysteine uniformely labelled on the sugar moiety. An enzymatic route from (U‐ 14 C) adenosine
Author(s) -
Guillerm G.,
Allart B.
Publication year - 1992
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580310911
Subject(s) - chemistry , homocysteine , adenosine , hydrolase , enzyme , stereochemistry , moiety , biochemistry
[(U‐ 14 C) S‐Ribosyl]‐L‐homocysteine has been prepared enzymatically from (U‐ 14 C) adenosine in two steps using S‐adenosyl homocysteine hydrolase (EC.3.31.1) and bacterial S‐adenosyl homocysteine nucleosidase (EC.3.2.2.9) as catalysts.