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Understanding the mechanism of sweet taste: Synthesis of tritium labeled guanidineacetic acids
Author(s) -
Nagarajan Srinivasan,
Kellogg Michael S.,
Dubois Grant E.,
Williams David S.,
Gresk Christopher J.,
Markos Charles S.
Publication year - 1992
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580310806
Subject(s) - chemistry , tritium , sweet taste , taste , reagent , mechanism (biology) , catalysis , organic chemistry , combinatorial chemistry , radiochemistry , biochemistry , physics , philosophy , epistemology , nuclear physics
Syntheses of tritium labeled guanidineacetic acid sweetener and a tritiated photoaffinty labeling reagent via the catalytic hydrogenation of the dibromo intermediates are described. These labeled compounds were required for the investigation of sweet taste mechanism.