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Synthesis of α‐ and γ‐tocopherols selectively labelled with deuterium
Author(s) -
Hughes L.,
Slaby M.,
Burton G. W.,
Ingold K. U.
Publication year - 1990
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580280909
Subject(s) - chemistry , bioavailability , tocopherol , deuterium , radiochemistry , vitamin e , metabolism , chromatography , stereochemistry , organic chemistry , biochemistry , pharmacology , antioxidant , medicine , physics , quantum mechanics
Four deuterium‐substituted α‐tocopherols (dideutero‐ RRR , nonadeutero‐ ambo , nonadeutero‐ all‐rac and undecadeutero‐ all‐rac ) and a dideutero‐ RRR ‐γ‐tocopherol have been synthesized for use in studies of the biokinetics, bioavailability and metabolism of vitamin E.