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Synthesis of trideuteromethyl‐3(5) pyrazoles
Author(s) -
Iranzo Gloria Y.,
Elguero José
Publication year - 1990
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580280810
Subject(s) - chemistry , acetylacetone , hydrazine (antidepressant) , hydrate , pyrazole , combinatorial chemistry , organic chemistry , biochemistry
The synthesis of 3,5‐bis (trideuteromethyl) pyrazole was achieved by reaction of perdeuterated acetylacetone with perdeuterated hydrazine hydrate. Some unsuccessful attempts using alternative routes are also described.