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Synthesis of [ 3 H] aminocyclopropane carboxylic acid (ACC) as a ligand for the glycine b receptor
Author(s) -
Dappen Michael S.,
Markos Charles S.,
Gresk Christopher J.,
Cordi Alex A.
Publication year - 1990
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580280714
Subject(s) - chemistry , glycine , ligand (biochemistry) , carboxylic acid , 1 aminocyclopropane 1 carboxylic acid , stereochemistry , receptor , glycine receptor , biochemistry , enzyme , amino acid , biosynthesis
The synthesis of [ 3 H] Aminocyclopropane carboxylic acid (ACC, 1) at high specific activity and high purity is described. The compound has been developed as a specific ligand for the Glycine‐B binding site.
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