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Tritium labelling by selective debromination
Author(s) -
Brundish Derek E.,
Kane Peter D.
Publication year - 1988
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580251210
Subject(s) - chemistry , labelling , bromine , chlorine , double bond , tritium , radiochemistry , halogenation , chlorine atom , organic chemistry , medicinal chemistry , biochemistry , physics , nuclear physics
Methods are described for tritiating compounds containing both chlorine or a double bond and bromine by highly‐selective debromination to give the chlorine‐containing or unsaturated 3 H‐compounds with specific activities of 10–28 Ci/mmol.