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Synthesis of acetaminophen‐d 4
Author(s) -
Johnston D.,
Elder D.
Publication year - 1988
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580251204
Subject(s) - chemistry , acetaminophen , yield (engineering) , nitrobenzene , nuclear chemistry , organic chemistry , catalysis , metallurgy , biochemistry , materials science
A synthetic procedure for acetaminophen‐d 4 (4′‐hydroxyacetanilide – 2′,3′,5′,6′‐d 4 ) is described. The preparation was achieved in two steps from nitrobenzene‐d 5 in an overall yield of 40%.