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Synthesis of perdeuterio‐1,4‐diazabicyclo[2,2,2]octane (DABCO‐ 2 H 12 )
Author(s) -
Gorman A. A.,
Standen M. C.
Publication year - 1988
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580250903
Subject(s) - dabco , chemistry , octane , singlet oxygen , quenching (fluorescence) , molecule , medicinal chemistry , bicyclic molecule , photochemistry , stereochemistry , oxygen , organic chemistry , fluorescence , physics , quantum mechanics
1,4‐Diazabicyclo[2,2,2]octane (DABCO) is an efficient quencher of singlet oxygen, O 2 ( 1 Δ g ), and is used as an indicator of O 2 ( 1 Δ g ) intermediacy in both chemical and biochemical oxidative processes. The quenching is physical in character and the fully deuteriated derivative, DABCO‐ 2 H 12 , is a molecule of potential mechanistic importance. Its synthesis with >98% isotopic purity is described.