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Synthese de la Letosteine: Marquee AU 14 C ET AU 35 S
Author(s) -
Nicolas Colette,
Gachon Francloise,
Faurie Michel
Publication year - 1985
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580220712
Subject(s) - chemistry , thiazolidine , carbon 14 , medicinal chemistry , stereochemistry , physics , quantum mechanics
LETOSTEINE, 2‐[1ethoxy carbonyl methylthio)‐ethyl] 4‐hydroxycarbonyl thiazolidine is labelled with either carbon‐14 or Sulfur‐35 on the following positions: 1 ‐ the carboxylic carbon of the ester function by means of chloro (1‐ 14 C)‐acetic acid. 1 ‐ the thiazolidinyl group by means of L‐( 35 S)‐cysteine.Specific activities are 0,373 mCi/mMole or 13,8 MBq/mMole for 14 C‐LETOSTEINE and 9,90 mCi/mMole or 366 MBq/mMole for 35 S‐LETOSTEINE.