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A facile microsynthesis of 14 C‐labelled picene
Author(s) -
Beermann Dieter,
Petrovic Peter,
Seidel Albrecht,
Oesch Franz
Publication year - 1984
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580210812
Subject(s) - chemistry , wittig reaction , yield (engineering) , phosphonium , phosphonium salt , aryl , salt (chemistry) , radiochemistry , medicinal chemistry , organic chemistry , combinatorial chemistry , alkyl , physics , thermodynamics
Microscale Wittig olefination of commercially available [7‐ 14 C]‐benzal dehyde of high specific radioactivity with aryl bromomethyl phosphonium salt and subsequent oxidative photocyclisation affords pure 14 C‐labelled picene in efficient yield.