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An evaluation of the introduction of stable nuclides of bromine into high specific activity radiobrominations
Author(s) -
Wilbur D. S.,
Garcia S. R.,
Adam M. J.,
Ruth T. J.
Publication year - 1984
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580210811
Subject(s) - bromine , nuclide , reagent , chemistry , oxidizing agent , radiochemistry , neutron activation , organic chemistry , neutron , nuclear physics , physics
An investigation has been carried out to evaluate the quantity of stable nuclides of bromine that might be introduced into the reaction mixtures of high specific activity radiobrominations from the reagents used. In the investigation neutron activation analyses were performed on the radionuclide solutions, solvents, oxidizing agents, and substrates that have been used in radiobromination reactions to determine the concentrations of bromine present. All of the reagents examined had detectable quantities of bromine. Among the reagents, a large variation in the concentrations of bromine was found. Due to the quantities of bromine found and the variability of bromine concentrations in the reagents, it is suggested that the reagents used in high specific activity radiobrominations be analyzed for bromine.