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Radioactively labelled epoxides. Part IV. Tritium labelled α‐ and β‐methyl styrene oxides
Author(s) -
Oesch Franz,
Sparrow Alan J.,
Platt Karl L.
Publication year - 1983
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580201111
Subject(s) - styrene , chemistry , tritium , styrene oxide , oxide , epoxide , radiochemistry , organic chemistry , nuclear chemistry , catalysis , copolymer , polymer , nuclear physics , physics
Tritium labelled α‐methyl styrene oxide (2‐methyl‐2‐phenyloxirane) and cis ‐ and trans ‐β‐methyl styrene oxides (Z‐ and E‐2‐methyl‐3‐phenyl oxirane) have been prepared using tritiated water as the inexpensive source of tritium. The two geometrical isomers of β‐methyl styrene oxide were synthesized by a sequence of reactions which led to stereochemically pure products, and obviated any need to separate the isomers.