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Syntheses of 1‐dodecyl‐d 25 phosphate
Author(s) -
Sniegoski Lorna T.,
White Edward
Publication year - 1983
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580200217
Subject(s) - chemistry , dodecanol , phosphate , deuterium , yield (engineering) , hydrogen phosphate , nuclear chemistry , catalysis , inorganic chemistry , medicinal chemistry , organic chemistry , physics , materials science , quantum mechanics , metallurgy
1‐Dodecyl‐d 25 phosphate was prepared from commercially available 1‐dodecanol‐d 26 . The 1‐dodecanol‐d 26 reacted with diphenyl phosphorochloridate to produce 1‐dodecyl‐d 25 diphenyl phosphate, which was reduced with hydrogen in the presence of Adams catalyst to give a 58.9 percent yield of 1‐dodecyl‐d 25 phosphate with 99.4 atom percent deuterium.