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[ 14 C]Senecionine and [ 14 C]isosenecionine from the pyrrolizidine alkaloid retrorsine
Author(s) -
Mattocks A. Robin
Publication year - 1983
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580200215
Subject(s) - chemistry , pyrrolizidine alkaloid , alkaloid , pyrrolizidine , stereochemistry
Retrorsine ( 1 ) has been oxidized to a mixture of two epimeric cyclic keto esters ( 2 ) which, [ 14 C]methylmagnesium iodide gave [18‐ 14 C]senecionine ( 3a ) and [18‐ 14 C] isosenecionine ( 3d ).