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Enzymatic synthesis of radio‐labeled selenocystine from labeled serine and selenide
Author(s) -
Dilworth Gregory L.
Publication year - 1982
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580191010
Subject(s) - chemistry , serine , selenocysteine , selenide , enzyme , biochemistry , stereochemistry , selenium , organic chemistry , cysteine
Selenocysteine can be formed enzymically from O‐acetylserine and sodium selenide by O‐acetylserine sulfhydrylase. The preparation of O‐acetylserine from serine and its conversion to selenocystine are described. These reactions can be used to synthesize [ 14 C], [ 3 H], or [ 75 Se]selenocystine.