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Reparation of 3 H‐, and 14 C‐labeled ethylmorphine
Author(s) -
Yost Yul,
Holtzman Jordan L.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181212
Subject(s) - chemistry , alkoxy group , group (periodic table) , medicinal chemistry , methyl group , stereochemistry , organic chemistry , alkyl
7,8‐Didehydro‐4,5‐epoxy‐3‐ethoxy‐17‐methyl( 3 H)‐, and −17‐methyl ( 14 C)morphinan‐6‐ol were prepared by substituting the N‐methyl group with/ a carbphenoxy group which was then either reduced with LiAl 3 H 4 or removed to remethylate the N‐atom with 14 CH 3 I.