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Deuterium exchange labelling of biologically important phenols, indoles and steroids
Author(s) -
Vining R. F.,
Smythe G. A.,
Long M. A.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181114
Subject(s) - chemistry , labelling , deuterium , yield (engineering) , phenols , indole test , chemical synthesis , organic chemistry , tritium , biological activity , steroid , hydrogen–deuterium exchange , biochemistry , in vitro , hydrogen , physics , nuclear physics , materials science , quantum mechanics , hormone , metallurgy
Deuterated analogues of various phenolic steroids, catechols and indole derivatives were prepared in high chemical yield by heating the relevant compound in D 2 O at 190°C for 24 hours.