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Synthesis of microamounts of ketones from carboxylic acids: 1‐phenoxy‐2‐butanones‐2‐ 14 ‐ 14 C
Author(s) -
Look Melvin
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181021
Subject(s) - chemistry , acetic acid , ketone , carboxylic acid , lithium (medication) , organic chemistry , medicinal chemistry , medicine , endocrinology
A technique using acetic acid as a co‐reactant for synthesizing microamounts of radiolabelled ketones from carboxylic acids with ethyl lithium is described. The acetic acid forms methyl ethyl ketone, a compound easily separated from the radiolabelled products.