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Separation of inorganic iodide in the analysis of some iodoorganic radiopharmaceuticals
Author(s) -
Lucka Barbara,
Siuda Andrzej
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181011
Subject(s) - chemistry , iodide , iodine , sodium iodide , ammonium iodide , aqueous solution , solvent , ammonium , radiochemistry , nuclear chemistry , chromatography , inorganic chemistry , organic chemistry
A paper chromatography technique using 33% w/v aqueous solution of ammonium sulphate as a solvent has been applied for fast separation of inorganic radioactive iodide from labelled organic compound in the analysis of some iodoorganic radiopharmaceuticals of common use. L‐triiodothyronine, L‐thyroxine, Rose Bengal and bromosulphthalein are retained at the starting spot while iodide migrates at R f 0.5. The separation is obtained at a development path of 5cm in about 10min. Sodium o‐iodohippurate, however, migrated at R f 0.4 and its separation from inorganic iodide was not achieved under the conditions employed.