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High specific activity [phenyl‐ 3 h]benzylpenicillin N‐ethylpiperidine salt
Author(s) -
Rosegay Avery
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180909
Subject(s) - chemistry , benzylpenicillin , salt (chemistry) , acetone , isotope dilution , penicillin , dilution , aqueous solution , specific activity , nuclear chemistry , radiochemistry , chromatography , organic chemistry , antibiotics , biochemistry , mass spectrometry , enzyme , physics , thermodynamics
The N‐ethylpiperidine salt of [ 3 H]penicillin G (31 Ci/mmole) was prepared and stored in acetone solution at −15°. The radiochemical purity, as determined by reverse isotope dilution assay, decreased about 12% over a period of one month, less than that expected for an aqueous solution.