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Synthesis of 1‐(3‐trideuteromethoxy‐4‐hydroxyphenyl)‐[1,2,2‐ 2 H 3 ]‐ethyleneglycol ([ 2 H 6 ]MHPG)
Author(s) -
Murray S,
Baillie T A,
Davies D S
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180808
Subject(s) - chemistry , stereochemistry , radiochemistry
The four stage synthesis of a hexadeuterated analogue of the noradrenaline metabolite 3‐methoxy‐4‐hydroxyphenylethylene glycol (MHPG) is described. The overall yield from 3‐trideuteromethoxy‐4‐hydroxyacetophenone is 29%.