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A novel synthesis of α‐N‐methyl‐ 14 C‐DL‐asparagine by generation of methylamine‐ 14 C in situ
Author(s) -
Tsou HweiRu
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180619
Subject(s) - methylamine , chemistry , yield (engineering) , hydrochloride , in situ , chemical synthesis , medicinal chemistry , organic chemistry , in vitro , materials science , metallurgy , biochemistry
Abstract A method is described by which methylamine‐ 14 C is qenerated from its hydrochloride by N,N‐diisopropylethylamine in the presence of maleamic acid to produce the title compound in high yield.