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A convenient synthesis of N G ‐mono[ 14 C‐methyl]‐L‐arginine
Author(s) -
AbouGharbia M.,
Paik W. K.,
Swern D.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180603
Subject(s) - chemistry , methyl iodide , arginine , yield (engineering) , ornithine , iodide , amino acid , stereochemistry , medicinal chemistry , organic chemistry , biochemistry , materials science , metallurgy
N G ‐Mono[ 14 C‐methyl]‐L‐arginine was prepared in a two‐step synthesis. N,S‐dimethylthiopseudouronium iodide [methyl‐ 14 C] was prepared in excellent yield and afforded the labelled amino acid on coupling with L‐ornithine.