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Synthesis of 14 C and 35 S labelled carbonyl sulfide
Author(s) -
Chengelis Christopher P.,
Neal Robert A.
Publication year - 1980
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580170619
Subject(s) - chemistry , potassium thiocyanate , carbonyl sulfide , yield (engineering) , sulfide , sulfuric acid , thiocyanate , potassium , inorganic chemistry , nuclear chemistry , medicinal chemistry , organic chemistry , radiochemistry , sulfur , materials science , metallurgy
Carbonyl sulfide (COS) was prepared by a replacement reaction from potassium thiocyanate (KSCN) in 50% sulfuric acid. 14 C‐COS or 35 S‐COS can be prepared by the same method, depending on the position of the label in the starting KSCN. The yield of the final product is in excess of 60%, and radiochemical purity was 99.5%.