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Synthesis of 3‐indolyl(1‐ 14 C)acetic, 3‐indolyl(2‐ 14 C) acetic and 3‐indolyl(1,2‐ 14 C 2 )acetic acids
Author(s) -
Viswanathan K. V.,
Ramaamurthy T. V.
Publication year - 1980
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580170516
Subject(s) - chemistry , acetic acid , glycolic acid , yield (engineering) , organic chemistry , lactic acid , materials science , biology , bacteria , metallurgy , genetics
The synthesis of 3‐indolylacetic acid labelled with 14 C in side chain carbon atoms has been effected using (1‐ 14 C)glycolic acid, (1,2‐ 14 C 2 )glycolic acid and (2‐ 14 C)glycolic acid in an yield of 40‐60%. Some of the parameters that affect the synthesis have been studied and the results are reported in this paper.