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Synthesis of Shikimic‐6‐ 13 C acid
Author(s) -
Hollstein Ulrich,
Mock David L.,
Sibbitt Randy R.,
Roisch Uta,
Lingens Franz
Publication year - 1980
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580170216
Subject(s) - shikimic acid , chemistry , acetic acid , phosphate , nuclear chemistry , stereochemistry , organic chemistry
Shikimic‐6‐ 13 C acid, 43 ± 5% enriched, was synthesized from 91% enriched acetic‐2‐ 13 C acid via 91% enriched phosphoenolpyruvic‐3‐ 13 c acid. The latter intermediate was condensed with erythrose‐4‐phosphate by a cell free extract of E . coli 83‐24.