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Carrier‐free 11 C Formaldehyde : An approach
Author(s) -
Berger G.,
Mazière M.,
Sastre J.,
Comar D.
Publication year - 1980
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580170107
Subject(s) - formaldehyde , chemistry , dehydrogenation , reagent , catalysis , mole , nuclear chemistry , organic chemistry
The different parameters of 11 C formaldehyde synthesis from 11 CO 2 have been systematically studied in order to improve yields, reproductibility and specific radioactivity. With modifications brought to gas and reagents purity, 11 CO 2 trapping system, target and dehydrogenation catalyst treatment, 100 to 200 mCi of 11 C formaldehyde are obtained at EOB + 10 mn, with a specific activity on the order of 600 mCi/μmole (maximum 1 Ci/μmole).