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A high yield synthesis of dimethylsulfide‐ d 6 , and preparation of chloro‐(dimethylsulfide‐ d 6 )gold(i) and trichloro(dimethylsulfide‐ d 6 )gold(III)
Author(s) -
Shaw C. Frank,
Cancro Margaret P.,
Butler Ian S.
Publication year - 1979
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580160605
Subject(s) - chemistry , yield (engineering) , triphenylphosphine , solvent , ligand (biochemistry) , medicinal chemistry , carbon tetrachloride , organic chemistry , materials science , receptor , metallurgy , catalysis , biochemistry
Dimethylsulfide‐ d 6 has been prepared in higher yield than reported previously by an improved method involving the reduction of dimethylsulfoxide‐ d 6 with triphenylphosphine in a solvent mixture of carbon tetrachloride and 2,2‐dimethoxydiethyl ether at 0°C. The high isotopic purity of the compound was demonstrated by its gas phase infrared and mass spectra. Its utility as a ligand in coordination chemistry was then shown by the synthesis of two typical gold complexes, viz ., chloro(dimethylsulfide‐ d 6 )gold(I) and trichloro(dimethylsulfide‐ d 6 )gold(III).