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Rapid synthsls of 14 C LABELLED 4(5)‐amino‐5(4)‐imidazole‐carboxamide
Author(s) -
Koltai E.,
Bánfi D.,
Szatmári I.,
HornyákHámori Maria,
Schawartz J.,
Szüts T.
Publication year - 1979
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580160516
Subject(s) - carboxamide , chemistry , imidazole , acetamide , hydrochloride , stereochemistry , medicinal chemistry , organic chemistry
4(5)‐Amino‐5(4)‐imidazole‐2‐ 14 C‐carboxamide was prepared in a two step synthesis. K 14 CN was converted into ethyl formimidate‐ 14 C hydrochloride, which was reacted with 2‐amino‐2‐amidino‐acetamide dihydrochloride to give the desired product.