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Syntheses de Phenyl‐2 Oxetannes marques au Deuterium et AU 13 C
Author(s) -
Schaal C.,
Ricard M.
Publication year - 1979
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580160510
Subject(s) - chemistry , benzaldehyde , deuterium , propanediol , medicinal chemistry , organic chemistry , catalysis , physics , quantum mechanics
Five mono, di, tri and pentadeuterated 2‐ phenyloxetanes were prepared either by tosylation and cyclisation of the corresponding 2‐phenyl propanediol (mono, di, tri, pentadeuterated) or from the benzoyl ethylacetate by exchange under acid conditions. The 2‐phenyloxetane 13 C was synthesized from benzaldehyde 13 C.