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Preparation of 3, 5‐dimethylpyrazole‐3, 5‐ 14 C and its hypoglycemic metabolite, 5‐methylpyrazole‐3‐carboxylic acid‐5‐ 14 C
Author(s) -
Thomas Richard C.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580150152
Subject(s) - chemistry , metabolite , carboxylic acid , stereochemistry , organic chemistry , biochemistry
3, 5‐Dimethylpyrazole‐3, 5‐ 14 C and its hypoglycemic metabolite, 5‐methylpyrazole‐3‐carboxylic acid‐5‐ 14 C, were each prepared by separate two‐step reaction sequences from acetone‐2‐ 14 C in 38% and 46% yields, respectively.