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Synthese von 3‐chlor‐4‐methyl‐[4‐ 14 C]‐7‐hydroxycumarin
Author(s) -
Müller J. P. H.,
Attar A.,
Kurth H.J.,
Bieniek D.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580150132
Subject(s) - chemistry , yield (engineering) , coumarin , radiochemistry , specific activity , nuclear chemistry , medicinal chemistry , organic chemistry , enzyme , materials science , metallurgy
Abstract The synthesis of 3‐chloro‐4‐methyl‐[4‐ 14 C]‐7‐hydroxy‐coumarin from ethyl [3‐ 14 C] acetoacetat is described. The overall radiochemical yield was 46%, after purification, at a specific activity of 5 mCi/mmol.